This is Paul. I work closely with Amy and help with Autoimmunity Research.

L-form bacteria are definitely part of the microbiota that makes patients sick with chronic disease, and Gerald Domingue has done a fine job of describing them. If you haven’t done so already, you may want to consider reading his textbook.

Research in l-forms may be forgotten by many, but like the abstract you post suggests, there are certain pockets where it is not. European scientists tend to be more interested in l-forms, as do researchers involved in veterinary science, interestingly.

Many of us expect that regard for l-forms will increase as more data comes out of the Human Microbiome Project.

Best,
Paul

Keywords: Spirochete cysts, Treponema pallidum, Borrelia burgdorferi, AIDS co-factor, immune suppression, STD, spirochetoses, Spirosymplokos, fossil spirochetes, spirochete life histories, Mixotricha paradoxa, round body reversion”

I have just discovered the work of Gerald Domingue which is very exciting. I am an evolutionary geographer with an interest in the extraordinarily common phenomena of “lost, forgotten or unknown science”.

I’m so sorry to hear about all your symptoms and diagnoses. I know what you must be pushing through and how desperate you must feel. I definitely agree that your symptoms are likely caused by an array of different chronic bacterial species including L-form bacteria. Our research indicates that nearly all diseases of “unknown” cause are actually bacterial in origin. What symptoms a person develops depends on what chronic species they accumulate and in what parts of their body.

It seems like your chronic bacterial load has been growing an spreading for many years. I personally had terrible candida, CFS and fibroymyalgia. I recovered from the diseases on the Marshall Protocol and experienced a potent bacterial die-off reaction called immunopathology that confirmed that my symptoms were indeed caused by bacteria. I am sure the same would prove true for you.

The fact that prednisone allows you to manage your symptoms somewhat is a huge clue that your various symptoms are all bacterial in origin. Prednisone works by slowing the immune system and subsequently release of painful inflammatory proteins secreted by the immune system in response to bacteria. The patient feels better, but never gets better – as your case seems to indicate.

In my opinion, you should definitely try the Marshall Protocol which was carefully created to target the bacteria, such as L-forms, that cause symptoms of “unknown” cause. If you do the treatment, you will experience a rise in symptoms after each antibiotic dose as your bacteria are killed (immunopathology). So that’s something you have to be willing and prepared for. However the ability to finally target the root cause of all your symptoms is great motivation to continue pressing forward.

If you kidneys are affected you may have a harder time dealing with immunopathology, as the kidneys deal with the toxins generated by bacterial death. You would need to work closely with your doctor and have your doctor discuss your case with Dr. Marshall in order to make sure your kidneys do not become overloaded as the treatment progresses. You may have to dose your antibiotics at a slower rate than some other people on the treatment and make sure to have frequent blood tests that record your kidney function. Benicar, one of the drugs used by the MP, actually protects the kidneys. This article about kidney function on the MP and the effects of Benicar on the kidneys would be important to read and show to your doctor:

http://bacteriality.com/2008/02/23/misconceptions/#6

The first step in getting started would be finding a doctor willing to put you on the MP. You can ask for a list of doctors in your area who administer the MP at the following link:

http://www.curemyth1.org (Th1 refers to diseases caused by bacteria, hence the name). The patient advocates on the site, who are volunteers, will give you the list and also answer any other questions you have about the MP free of charge.

Here are the Phase 1 guidelines which contain Dr. Marshall’s phone number if you doctor is willing to call him:

http://www.marshallprotocol.com/forum2/2275.html

Here is a list of Dr. Marshall and staff’s published papers and conference speeches that he/she may want to review:

http://mpkb.org/doku.php#publications_presentations

If you don’t feel you fully understand the MP, watch the following video which give a good overview of the treatment and the science that forms its backbone:

http://bacteriality.com/2008/05/07/mpintro/

I recommend posting about your situation on http://www.curemyth1.org and talking to some of the advocates about how to start the treatment.

Good luck!

Amy

I have just come accross your site after days of sitting on the computer trying to find out information on a disease I have been diagnosed with. I have FSGS (Focal Segemental Glomeruliolscerlosios) and nephrotic syndrome. I have been told its idopathic (no known cause) and been put on steriods (Predisione) with only a 50% chance of success! With the outlook of loosing all kidney function. I truely believe I have an autoimmune disease or this L-form bacteria. I have been sick for as long as I can remember. With no help from anyone – I self diagnosed with CFS and Fibroymyalgia, bowel candida, endometriosis and have multiple food and chemical sensitivies. Can you please throw some light on this. I am totally devasted – mother of 3 young girls. (I am 40years old) Thank you.

Thanks so much for posting when I know it must be very draining for you. I’m so glad that you are working with your doctor to start the MP. It will take time, but in the end I’m convinced that your will get your life back and feel your age or even better.

There are many other people who started the MP in a very debilitated state and are making good progress. Plus, once you are on the MP there is usually a change in attitude. Instead of getting sicker each day, with every day spent on the MP you are getting a little bit better. As a friend used to tell me, “Once on the MP, every night you go to sleep with less bacteria then you did the day before.” From now on you will be headed in the right direction.

I know how hard it is to be an active and gregarious person, only to fall ill with a disease that prevents you from doing anything. I was young when I got sick, but became very ill very fast until I was completely bedridden – and just like you had symptoms in every single area of my body. I got very sick right during my last year of college and for a long time I was totally disconnected from other people and any sort of activity.

Now I am becoming more active and spending a great deal of time with family and friends. I never thought it would be possible before the MP.

Best,

Amy

Just found this article through the MP website and found it very interesting and helpful. I’m so sick, I can hardly email, but wanted to thank you for the information you are making possible. I know it will help me cope. I am 64 and have been mostly “un-diagnosably” sick for 50+ years–particularly bad for the past 4-5 years. I’ve finally found a good doctor and will start the MP soon. Unfortunatly, my doctor prescribed Vit D 3 months ago before he discovered the MP, so I’m trying to get D levels back down now. It was 7 to start with, which seems now to be a good place for the MP, but now is 60! He’s fairly certain I have Lyme plus many other co-infections. Interesting about Pyelonephritis as I had a fairly bad case of it as a teenager and my brother lost a kidney to it. I have every symptom known to man and am now almost totally debilitated. Terribly depressed as I’m an active person in my heart and spirit and do not at all identify with being 64!

I haven’t posted on the MP site yet–just haven’t had the energy; but I will make myself do so very soon.

I’m looking forward to reading all else that you submitted.

Abigail

Your B12 injections and other medications are definitely just covering up your symptoms and not targeting what really making you sick. What is making you sick are different species of L-form bacteria, many of those which Domingue investigated.

The only treatment that will kill these bacteria and allow you to recover your health is the Marshall Protocol. In order to do the treatment, all you need to do is find a doctor who will prescribe you the necessary medications (antibiotics and Benicar). Then you work with him, but can also post your symptoms on the Marshall Protocol study site and you can be guided my experienced nurse moderators on how to best manage the immunopathology that results from taking the antibiotics.

Right now, what you should do is go to the following website:

http://www.curemyth1.org (Th1 disease is the name given to illnesses caused by L-form bacteria, hence the name Cure My Th1)

You an post all your questions about the Marshall Protocol – how to find a doctor, or how to work with your current doctor etc – on that site and they will be answered by patient advocates. They will guide you through the process of getting started.

You might want to take a look at the interview with Carole Morgan on this site. She was also a school teacher, also had fibromyalgia, and has gotten her life back thanks to the MP. The same will be true for you if you start the treatment.

http://bacteriality.com/2007/11/08/interview8/

Best,

Amy

I fully agree with his opinion about “ethics of scientific writing”.

Nadya Markova, PhD
Institute of Microbiology,
Bulgarian Academy of Sciences
Sofia, BULGARIA