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	<title>Comments on: Duke University researchers connect vitamin D with brain lesions</title>
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		<title>By: Amy Proal</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-18527</link>
		<dc:creator>Amy Proal</dc:creator>
		<pubDate>Sun, 15 Nov 2009 04:33:07 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-18527</guid>
		<description>Dear Dan,

The researchers specifically performed an entire study before this one to rule out the possibility that fat could have played a role in lesions. While it’s possible that another component of milk could be contributing to the lesions, many variables were analyzed and vitamin D was the only one that was statistically associated with the lesions. Because it was significant, unless the research was flawed, it has a relationship to the development of lesions.

I have no idea if they used D2 and D3. You may want to email the researchers.

From where we stand vitamin D2 and D3 are the same in terms of their ability to suppress the immune response. In the future, please don’t post your comment twice. There is a message right above the comment box that says it may take a while to get back to you, because I am school right now.

Thanks for your patience.

Amy</description>
		<content:encoded><![CDATA[<p>Dear Dan,</p>
<p>The researchers specifically performed an entire study before this one to rule out the possibility that fat could have played a role in lesions. While it’s possible that another component of milk could be contributing to the lesions, many variables were analyzed and vitamin D was the only one that was statistically associated with the lesions. Because it was significant, unless the research was flawed, it has a relationship to the development of lesions.</p>
<p>I have no idea if they used D2 and D3. You may want to email the researchers.</p>
<p>From where we stand vitamin D2 and D3 are the same in terms of their ability to suppress the immune response. In the future, please don’t post your comment twice. There is a message right above the comment box that says it may take a while to get back to you, because I am school right now.</p>
<p>Thanks for your patience.</p>
<p>Amy</p>
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	<item>
		<title>By: Dan</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-18524</link>
		<dc:creator>Dan</dc:creator>
		<pubDate>Sun, 15 Nov 2009 03:38:36 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-18524</guid>
		<description>Amy,

Thank you for this

I&#039;d like to know what kind of Vit D they used. Fortified Vit D in milk is Synthetic Vit D - D2. The information being out on the benefits of Vit D is D3.

Second, was it synthetic D2 that was supplemented or natural Vit D3?

Third, drinking pasteurized milk from sick cows on factory farms that are fed GMO corn and soy, ground up roadkill, rBGH, antibiotics and steroids is poison IMO.

So this in my opinion, although interesting, doesn&#039;t hold a lot of weight....Payne and team had found that individuals who consumed more high-fat dairy products had more brain lesions than those who did not follow such a diet but determined that fat intake in general was not a significant factor. However vitamin D is found in high fat dairy products, and a large number of dairy products are fortified with extra vitamin D. Hence the team’s idea to investigate the effect of vitamin D on brain lesions.

How do the researchers know it wasn&#039;t something else in the cow&#039;s milk like bovine spongiform that is causing these lesions?

I haven&#039;t had pasteurized milk in almost 2 decades an dont recommend it for my clients.

Would you please comment--- thank you Amy!!

Dan</description>
		<content:encoded><![CDATA[<p>Amy,</p>
<p>Thank you for this</p>
<p>I&#8217;d like to know what kind of Vit D they used. Fortified Vit D in milk is Synthetic Vit D &#8211; D2. The information being out on the benefits of Vit D is D3.</p>
<p>Second, was it synthetic D2 that was supplemented or natural Vit D3?</p>
<p>Third, drinking pasteurized milk from sick cows on factory farms that are fed GMO corn and soy, ground up roadkill, rBGH, antibiotics and steroids is poison IMO.</p>
<p>So this in my opinion, although interesting, doesn&#8217;t hold a lot of weight&#8230;.Payne and team had found that individuals who consumed more high-fat dairy products had more brain lesions than those who did not follow such a diet but determined that fat intake in general was not a significant factor. However vitamin D is found in high fat dairy products, and a large number of dairy products are fortified with extra vitamin D. Hence the team’s idea to investigate the effect of vitamin D on brain lesions.</p>
<p>How do the researchers know it wasn&#8217;t something else in the cow&#8217;s milk like bovine spongiform that is causing these lesions?</p>
<p>I haven&#8217;t had pasteurized milk in almost 2 decades an dont recommend it for my clients.</p>
<p>Would you please comment&#8212; thank you Amy!!</p>
<p>Dan</p>
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	<item>
		<title>By: Amy Proal</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-18509</link>
		<dc:creator>Amy Proal</dc:creator>
		<pubDate>Sat, 14 Nov 2009 20:44:41 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-18509</guid>
		<description>Thanks Brian,

Thanks for writing.  I would run like mad from someone trying to give me a 600,000 IU injection of D!  Whoa!  I definitely hope that the vitamin D community can begin to better mobilize to understand the implications of supplementation with a secosteroid.

Take care,

Amy</description>
		<content:encoded><![CDATA[<p>Thanks Brian,</p>
<p>Thanks for writing.  I would run like mad from someone trying to give me a 600,000 IU injection of D!  Whoa!  I definitely hope that the vitamin D community can begin to better mobilize to understand the implications of supplementation with a secosteroid.</p>
<p>Take care,</p>
<p>Amy</p>
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		<title>By: Brian</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-18504</link>
		<dc:creator>Brian</dc:creator>
		<pubDate>Sat, 14 Nov 2009 20:17:31 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-18504</guid>
		<description>Great site Amy thanks for your work. The contrast of scientists opinions on Vit D is amazing - Life Extension (www.LEF.org ) has an article on it and some doctors are giving IM injections of up to 600,000 iu of Vit. D. Talk about a difference of opinion. I doubt they are as mainstream doctors would say &#039;quacks&#039; just take a quick look at the Board of 

I hope we can get to the bottom of this and see how much Vit. D is optimal!</description>
		<content:encoded><![CDATA[<p>Great site Amy thanks for your work. The contrast of scientists opinions on Vit D is amazing &#8211; Life Extension (www.LEF.org ) has an article on it and some doctors are giving IM injections of up to 600,000 iu of Vit. D. Talk about a difference of opinion. I doubt they are as mainstream doctors would say &#8216;quacks&#8217; just take a quick look at the Board of </p>
<p>I hope we can get to the bottom of this and see how much Vit. D is optimal!</p>
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	<item>
		<title>By: Amy Proal</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-18335</link>
		<dc:creator>Amy Proal</dc:creator>
		<pubDate>Mon, 26 Oct 2009 01:14:54 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-18335</guid>
		<description>Hi Bowman,

How many other studies on vitamin D measure vitamin K? If you feel so strongly that vitamin K needs to be measured in every study that measures vitamin D&#039;s effects on disease, I assume you&#039;re prepared to stop referring to all of the pro-vitamin D studies which meet that criterion.

The brain lesions occurred in the presence of a low level vitamin D? That only suggests a trend where more brain lesions would occur with vitamin D unless you really expect vitamin D can, at higher levels, ameliorate the very problem that it caused. Have you read the full text? This group at Duke did good work. I see no need to criticize it for the factors you describe.

Best,
Amy</description>
		<content:encoded><![CDATA[<p>Hi Bowman,</p>
<p>How many other studies on vitamin D measure vitamin K? If you feel so strongly that vitamin K needs to be measured in every study that measures vitamin D&#8217;s effects on disease, I assume you&#8217;re prepared to stop referring to all of the pro-vitamin D studies which meet that criterion.</p>
<p>The brain lesions occurred in the presence of a low level vitamin D? That only suggests a trend where more brain lesions would occur with vitamin D unless you really expect vitamin D can, at higher levels, ameliorate the very problem that it caused. Have you read the full text? This group at Duke did good work. I see no need to criticize it for the factors you describe.</p>
<p>Best,<br />
Amy</p>
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	<item>
		<title>By: Bowman</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-18333</link>
		<dc:creator>Bowman</dc:creator>
		<pubDate>Sun, 25 Oct 2009 21:06:58 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-18333</guid>
		<description>Some obvious problems with this study:

First, the level of of vitamin K was not tested. Vitamin K is a necessary co-factor for vitamin D that potentially prevents the negative effects of increased calcium transport. Very recent research indicates that vitamin K works to break down the type of calcified plaque that is often associated with cardiovascular disease.

Second, the maximum level of vitamin D supplementation referred to in the study (around 1000 IU/day) is a trivial amount, given that most people make about 1,000 IU per minute when exposed to sunlight.

Third, the study only used intake of vitamin D, not plasma levels of 25-[OH]D, to determine physiological vitamin D status. There is no guarantee that those who took more vitamin D actually had elevated levels of vitamin D in their systems. Many people, especially the elderly, may not be as effective at absorbing dietary nutrients (including oral supplements) as younger people.

You guys need to work harder at proving your point, instead of tearing down the opposition by pointing out flawed studies such as this.</description>
		<content:encoded><![CDATA[<p>Some obvious problems with this study:</p>
<p>First, the level of of vitamin K was not tested. Vitamin K is a necessary co-factor for vitamin D that potentially prevents the negative effects of increased calcium transport. Very recent research indicates that vitamin K works to break down the type of calcified plaque that is often associated with cardiovascular disease.</p>
<p>Second, the maximum level of vitamin D supplementation referred to in the study (around 1000 IU/day) is a trivial amount, given that most people make about 1,000 IU per minute when exposed to sunlight.</p>
<p>Third, the study only used intake of vitamin D, not plasma levels of 25-[OH]D, to determine physiological vitamin D status. There is no guarantee that those who took more vitamin D actually had elevated levels of vitamin D in their systems. Many people, especially the elderly, may not be as effective at absorbing dietary nutrients (including oral supplements) as younger people.</p>
<p>You guys need to work harder at proving your point, instead of tearing down the opposition by pointing out flawed studies such as this.</p>
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	<item>
		<title>By: Amy Proal</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-8204</link>
		<dc:creator>Amy Proal</dc:creator>
		<pubDate>Sun, 29 Jun 2008 18:48:18 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-8204</guid>
		<description>Hi Zawy,

Wait, are you seriously telling me that people with increased brain lesions, the presence of which lead to numerous devastating conditions including death itself are going to be live healthier lives than those people not supplementing with vitamin D?  

It&#039;s clear you have not even looked at Marshall&#039;s groundbreaking model of vitamin D metabolism despite the fact that it is discussed in great deal on this site.  I suggest actually reading the articles and papers that describe how the different forms of vitamin D actually affect the innate immune response before jumping to conclusions.  Your comment simply does not make sense in the context of what is now understood about vitamin D&#039;s actions.

Take a look at Dr. Marshall&#039;s recent paper published in BioEssays in order to better understand how vitamin D supplementation negatively affects the population at whole and particularly people with chronic disease.

http://TrevorMarshall.com/BioEssays-Feb08-Marshall-Preprint.pdf 

Furthermore, Marshall&#039;s many papers, the plethora of data derived from our phase II trial, and the number of prestigious conferences at which Marshall is presenting his model of vitamin D metabolism make it abundantly clear that what he is putting forth is not a &quot;speculative theory.&quot;  It is based on decades of molecular modeling research that you, clearly, have failed to follow.

Best,

Amy</description>
		<content:encoded><![CDATA[<p>Hi Zawy,</p>
<p>Wait, are you seriously telling me that people with increased brain lesions, the presence of which lead to numerous devastating conditions including death itself are going to be live healthier lives than those people not supplementing with vitamin D?  </p>
<p>It&#8217;s clear you have not even looked at Marshall&#8217;s groundbreaking model of vitamin D metabolism despite the fact that it is discussed in great deal on this site.  I suggest actually reading the articles and papers that describe how the different forms of vitamin D actually affect the innate immune response before jumping to conclusions.  Your comment simply does not make sense in the context of what is now understood about vitamin D&#8217;s actions.</p>
<p>Take a look at Dr. Marshall&#8217;s recent paper published in BioEssays in order to better understand how vitamin D supplementation negatively affects the population at whole and particularly people with chronic disease.</p>
<p><a href="http://TrevorMarshall.com/BioEssays-Feb08-Marshall-Preprint.pdf" rel="nofollow">http://TrevorMarshall.com/BioEssays-Feb08-Marshall-Preprint.pdf</a> </p>
<p>Furthermore, Marshall&#8217;s many papers, the plethora of data derived from our phase II trial, and the number of prestigious conferences at which Marshall is presenting his model of vitamin D metabolism make it abundantly clear that what he is putting forth is not a &#8220;speculative theory.&#8221;  It is based on decades of molecular modeling research that you, clearly, have failed to follow.</p>
<p>Best,</p>
<p>Amy</p>
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	<item>
		<title>By: zawy</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-8137</link>
		<dc:creator>zawy</dc:creator>
		<pubDate>Sat, 28 Jun 2008 16:50:21 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-8137</guid>
		<description>The only problem is that people are much more likely to get sick and die if they get less sunlight or ingest vitamin D.  speculative theory is great, but in medicine even more than in science, observation in a population of the end result overrides exciting theories.   If they follow these 232 people, they&#039;ll see the high vitamin D people were much more likely to live healthier and longer.</description>
		<content:encoded><![CDATA[<p>The only problem is that people are much more likely to get sick and die if they get less sunlight or ingest vitamin D.  speculative theory is great, but in medicine even more than in science, observation in a population of the end result overrides exciting theories.   If they follow these 232 people, they&#8217;ll see the high vitamin D people were much more likely to live healthier and longer.</p>
]]></content:encoded>
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	<item>
		<title>By: Amy Proal</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-2933</link>
		<dc:creator>Amy Proal</dc:creator>
		<pubDate>Fri, 11 Apr 2008 13:52:17 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-2933</guid>
		<description>Hi Jim,

You can definitely fight and then recover from MS thanks to the treatment described on this website.  It&#039;s called the Marshall Protocol, and is part of phase II trials monitored by the FDA.  Patients on the treatment use pulsed, low-dose antibiotics and a medication that activates the immune system to gradually wear away at the bacteria we now understand causes MS and other inflammatory diseases.  

The Marshall Protocol is being used by doctors around the world and over 200 medical professionals are members of the study site.  Patients who start the treatment receive guidance, free of charge, from nurse moderators in exchange for reporting symptoms in a weekly progress report.  The treatment is run by the non-profit organization Autoimmunity Research Foundation.  Here is their website:

http://autoimmunityresearch.org/

The following two articles describe the Marshall Protocol in greater detail:

&quot;About the Marshall Protocol&quot;

http://bacteriality.com/about-the-mp/

&quot;Getting it right, how to correctly target L-form and biofilm bacteria&quot;

http://bacteriality.com/2007/10/11/antibiotics/

The bacteria implicated in MS are both biofilm bacteria and also L-form bacteria - bacteria that have mutated from their classical form and lost their cell walls.  They are able to live inside the cells of the immune system where they cannot be killed by standard antibiotic therapy.  These bacteria have been studied for over a century but have been largely ignored because they don&#039;t grow under normal laboratory conditions.  Read more about them here:

&quot;Understanding L-form bacteria&quot;

http://bacteriality.com/2007/08/15/l-forms/

Here is an interview with an MP doctor that I highly recommend you read:

&quot;Interview with Dr. Greg Blaney&quot;

http://bacteriality.com/2007/10/31/blaney/

There are many people on the MP with MS, all of whom are responding to the treatment.  More information about the treatment can also be found on the study site itself.  A good place to start reading is at the following forum:

&quot;Essential information about the MP&quot;

http://www.marshallprotocol.com/forum2/  

I&#039;m sure you have more questions about the Marshall Protocol.  The best place to ask them is at the following website:

www.curemyth1.org (Th1 refers to diseases caused by L-form bacteria, hence the name Cure My Th1).  You questions will be answered free of charge by patient advocates.

This is a curative treatment that offers serious hope for people with MS.  Kill the bacteria at the heart of your disease and you can become healthy once again.

Good luck!

Amy</description>
		<content:encoded><![CDATA[<p>Hi Jim,</p>
<p>You can definitely fight and then recover from MS thanks to the treatment described on this website.  It&#8217;s called the Marshall Protocol, and is part of phase II trials monitored by the FDA.  Patients on the treatment use pulsed, low-dose antibiotics and a medication that activates the immune system to gradually wear away at the bacteria we now understand causes MS and other inflammatory diseases.  </p>
<p>The Marshall Protocol is being used by doctors around the world and over 200 medical professionals are members of the study site.  Patients who start the treatment receive guidance, free of charge, from nurse moderators in exchange for reporting symptoms in a weekly progress report.  The treatment is run by the non-profit organization Autoimmunity Research Foundation.  Here is their website:</p>
<p><a href="http://autoimmunityresearch.org/" rel="nofollow">http://autoimmunityresearch.org/</a></p>
<p>The following two articles describe the Marshall Protocol in greater detail:</p>
<p>&#8220;About the Marshall Protocol&#8221;</p>
<p><a href="http://bacteriality.com/about-the-mp/" rel="nofollow">http://bacteriality.com/about-the-mp/</a></p>
<p>&#8220;Getting it right, how to correctly target L-form and biofilm bacteria&#8221;</p>
<p><a href="http://bacteriality.com/2007/10/11/antibiotics/" rel="nofollow">http://bacteriality.com/2007/10/11/antibiotics/</a></p>
<p>The bacteria implicated in MS are both biofilm bacteria and also L-form bacteria &#8211; bacteria that have mutated from their classical form and lost their cell walls.  They are able to live inside the cells of the immune system where they cannot be killed by standard antibiotic therapy.  These bacteria have been studied for over a century but have been largely ignored because they don&#8217;t grow under normal laboratory conditions.  Read more about them here:</p>
<p>&#8220;Understanding L-form bacteria&#8221;</p>
<p><a href="http://bacteriality.com/2007/08/15/l-forms/" rel="nofollow">http://bacteriality.com/2007/08/15/l-forms/</a></p>
<p>Here is an interview with an MP doctor that I highly recommend you read:</p>
<p>&#8220;Interview with Dr. Greg Blaney&#8221;</p>
<p><a href="http://bacteriality.com/2007/10/31/blaney/" rel="nofollow">http://bacteriality.com/2007/10/31/blaney/</a></p>
<p>There are many people on the MP with MS, all of whom are responding to the treatment.  More information about the treatment can also be found on the study site itself.  A good place to start reading is at the following forum:</p>
<p>&#8220;Essential information about the MP&#8221;</p>
<p><a href="http://www.marshallprotocol.com/forum2/" rel="nofollow">http://www.marshallprotocol.com/forum2/</a>  </p>
<p>I&#8217;m sure you have more questions about the Marshall Protocol.  The best place to ask them is at the following website:</p>
<p><a href="http://www.curemyth1.org" rel="nofollow">http://www.curemyth1.org</a> (Th1 refers to diseases caused by L-form bacteria, hence the name Cure My Th1).  You questions will be answered free of charge by patient advocates.</p>
<p>This is a curative treatment that offers serious hope for people with MS.  Kill the bacteria at the heart of your disease and you can become healthy once again.</p>
<p>Good luck!</p>
<p>Amy</p>
]]></content:encoded>
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	<item>
		<title>By: James M.  Trammell</title>
		<link>http://bacteriality.com/2007/10/24/brain_lesions/comment-page-1/#comment-2913</link>
		<dc:creator>James M.  Trammell</dc:creator>
		<pubDate>Thu, 10 Apr 2008 23:58:16 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/2007/10/24/brain_lesions/#comment-2913</guid>
		<description>I&#039;m learning.  I have MS.  Point me at any information that will help me fight this crippler.

Jim</description>
		<content:encoded><![CDATA[<p>I&#8217;m learning.  I have MS.  Point me at any information that will help me fight this crippler.</p>
<p>Jim</p>
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