Considering that there are trillions of bacteria in the gut, I can see how someone might try to argue that the immunopathology experienced by MP patients might simply result from killing gut bacteria.

However, the argument makes little sense if you think about the fact that die-off symptoms occur in the area in which bacteria are being killed. So if my eyes become inflamed after a dose of MP antibiotics, it’s an incredible stretch for me to attribute the rise in inflammation to gut bacterial death. In fact, the only logical explanation for the increases inflammation in my eyes would be that bacteria are indeed dying in the eyes themselves.

One of the great parts about the MP is that is relatively predictable. In general, bacterial die-off causes patients to experience a rise in those symptoms with which they are already familiar. Such immunopathology occurs in many areas other than the gut, making it clear that people are killing bacteria in other areas of the body, and bacteria that are directly causing their disease symptoms in the first place.

I suppose that if a person simply feels an overall sense of malaise in response to the MP antibiotics then one could hypothesize they are simply killing gut bacteria, but based on the associations described above that seems highly unlikely.

We have a lot to learn about gut bacteria. How many of them are actually beneficial and how many of them simply place an extra load on the innate immune system? I plan to put up an article in the coming weeks about the Human Microbiome project. The article will touch on the subject of gut bacteria in greater detail.

Best,

Amy

Parasitism and symbiotic living are still somewhat a mystery to todays science. And pleomorphism is almost at the edge of “forgotten, forbidden” area. Look at the viruses inside the bacteria, bacteria inside the parasites and parasites inside the animals or humans … I am curious what your opinions are on such theme as you are a skilled biologist (if you have some time to comment, thx).
Take care!
Petr

When you approach the MP, I encourage you to let go of the thinking that spending so much time in the troubled world of chronic disease has caused you to develop.

Why can there not be a “one-size-fits-all” treatment? Of course every patient on the MP has to dose their antibiotics at different rates depending on their bacterial loads, use different antibiotics at different times depending on what species of bacteria they harbor, and progress with all aspects of the treatment at different speeds.

But the fact that all chronic inflammatory disease are caused by a vast microbiota of chronic ideopathic biofilm-like and L-form bacteria CAN be applied to a “one-size-fits-all” model.

Think about it. There are hundreds of bacterial forms that cause acute infections. Penecillin is effective against many of them. Then add four more antibiotics in combination with penecillin (the way the MP uses four other pulsed, low-dose antibiotics besides minocycline) and there are very, very few bacterial species that can survive the onslaught.

Of course that scenario involves acute bacterial forms, and we know that the beta-lactams actually foster the creation of L-form bacteria. But my point is that the MP uses a broad spectrum of antibiotics that were carefully chosen based on a tremendous amount of molecular data. Together, the antibiotics, when taken in so many different combinations, block the 70S ribosome that any chronic pathogen needs to survive in a plethora of ways. The statistical chance that a chronic bacterial form could survive all these different ribosomal blockades is next to zero.

So yes, anyone suffering from a disease caused by chronic bacterial forms can benefit from the MP. And data from the MP study site clearly shows that people with nearly every inflammatory disease are experiencing immunopathology in response to the MP antibiotics.

The Marshall Protocol has an 100% response rate. That means that essentially every person - regardless of what specific disease they have - has experienced the bacterial die-off reaction called immunopathology. Everyone to start the MP has made it clear they have bacteria to kill.

The only reason that the MP doesn’t work for some people is because it works TOO well. Some people have such high bacterial loads and are so weak that they simply cannot tolerate strong immunopathology. Also, the kidneys and liver must be functioning if the body is to get rids of the toxins created by immunopathology. Some patients have livers or kidneys that are so infected with bacteria that the organs can simply not handle the die-off reaction.

So yes, in some situations, people cannot do the MP. But it’s not because they don’t have a disease caused by chronic persistent bacterial forms - it’s simply because their bodies are so sick that they don’t have the strength to kill off the pathogens making them sick.

This is not a new confining paradigm. Whereas during the past decades doctors have thought that the answer to disease could be found in our genes we now understand that essentially all chronic diseases are caused by a wide microbiota of chronic pathogens.

There will be much more exploration as we continue to identify these specific pathogens and learn more about them. But for now, all we need to know is that the MP can effectively kill them.

So do keep an open mind and read as much as you can about the molecular science that forms the basis of the MP and don’t resist the idea that the new paradigm shifts we are dealing with here have the potential to affect millions of lives.

Have you seen the video I just put up about the MP. If you haven’t I recommend watching it as it helps all the details of the treatment fall into place. Here’s the link:

http://bacteriality.com/2008/05/07/mpintro/

Best,

Amy

My feeling is that the infectious burdens are different, the immune systems are different in response, and doctors and patients have to feel their way along to see which kind of treatment will work for individual cases. This is hard to do because everyone wants one answer to be the right one, and the heck with this troublesome empirical stuff.

Am uncomfortable with any standard treatment, even if it is newer and does think outside the box of current treatment. Don’t want to discourage this kind of exploration, just don’t want a new confining paradigm.

It does make sense that chronic disease treatment might be different from acute.

You can request a list of MP doctors in Europe and the UK at the following link from the Marshall Protocol study site. Here are the instructions:

http://www.marshallprotocol.com/forum11/11348.html

If none of the doctors on the list are taking new patients or none of them work near you, I recommend going to the Marshall Protocol study site and searching for other members on the treatment who live in the UK. You can them send them a private message and ask who their doctor is. Hopefully you might be able to set up an appointment with the same physician. Search for MP members in the UK at this link:

http://snipr.com/mpunitk

If after the above efforts you still can’t find a doctor, post about your situation at the following website;

http://www.curemyth1.org (Th1 refers to diseases caused by L-form bacteria, hence the name Cure My Th1). The patient advocates on that site, who volunteer for the non-profit agency that runs the Marshall Protocol, will give you further advice on how to find a doctor.

Good luck and I’m so glad that your other family members may also be able to benefit from the MP.

Best,

Amy

am trying to find a doctor in UK to prescribe for me .
Have 3 other family members with disease

sesame

My name is Amy. I write the pieces for this site and interviewed Dr. Blaney. Maybe I can help you find a doctor.

First, you should request a list of doctors that already have patients on the MP who work in Europe. Hopefully there are some in Germany. You can request that list through the Marshall Protocol study site at this link:

http://www.marshallprotocol.com/forum11/11348.html

If the list does not show a doctor in your area, I would go onto the Marshall Protocol study site and search for other members that live in Germany. You can search at this link: snipr.com/germanmp

Finally, if nobody on the site can help you find a doctor in your area, I recommend that you do your best to convince a new doctor to let you try the MP. You can present him/her with the following packet of information that was created for MP physicians:

http://www.ginariggio.com/MP/phase1guide.html

If you do present the packet to a doctor, make sure you have read as much information on this site and on the Marshall Protocol study site so that you can be prepared to answer his/her questions.

If you need help understanding the MP in greater detail a good place to ask questions about the treatment is at the following website:

http://www.curemyth1.org (Th1 refers to diseases caused by L-form bacteria, hence the name Cure My Th1). The patient advocates on that site, who volunteer for the non-profit that runs the MP, will answer your questions free of charge.

Best,

Amy

I am from Germany and suffering from Sarkoidose and Fibromyalgie. Would like to try MP, but can´t find any doctor for this treatment here.

Do you know anyone here in Germany for MP?

Thanks for your help/answer.

I don’t think Dr. Blaney is worried about that issues at all. He clearly stated that one of the main reasons he is CONTINUING the antibiotics is to get rid of the tinnitus - meaning he thinks it’s caused by bacteria and returns as a result of immunopathology.

I’ve been on MP for nearly 3 years and I have still have tinnitus, although it has gotten progressively better, again suggesting that as I kill more bacteria it’s becoming less of a problem.

I even remember reading that Dr. Marshall also suffered from tinnitus but it has resolved completely, and he’s still taking minocycline.

So I personally think you probably just need more time to fully kill the bacteria causing the symptom.

Best,

Amy