Also, some claim Noni and Grapefruit seed extract works….any comments?

Interesting. One of the principles in that article is Randall Wolcott. If you do a Google search for Randall Wolcott, the #1 hit is Amy’s interview with him:
http://bacteriality.com/2008/04/13/wolcott/

So, yes indeed we have heard about Xylitol before.

However, the problem with Marshall Protocol patients isn’t generating bacterial die-off but controlling the reaction. That said, it may be worth giving those few patients who are non-responders xylitol and seeing if that can lead to bacterial killing. This might be an avenue we will research in time….

Best,
Paul

http://discovermagazine.com/2009/jul-aug/17-slime-city-germs-talk-each-other-plan-attacks/article_view?b_start:int=2&-C=

Thank you for your interest in our research. Borrelia is definitely a very hardy pathogen that we would expect would be able to survive in biofilms. Over the course of the next few years, Autoimmunity Research Foundation, which is the organization I work with, is hoping to run in which we will look at the DNA of the infected cells in patients with chronic disease. This study is still in the planning stages, but, in time, could eventually better help us understand how Borrelia survive in the body and in a biofilm-like environment.

Meanwhile, there is research suggesting that the low pulsed manner with which antibiotics are administered is much more effective at targeting bacteria in biofilms than standard regular doses of antibiotics or antibiotics taken in an IV form. Our own clinical data also shows people reporting improvement and recovery from Lyme disease thanks to therapy with the Marshall Protocol. So, if you think you may harbor Borrelia, and you want to target Borrelia in the biofilm state, looking into the MP may be a worthwhile option.

Best,
Amy

Thanks for this article. And I hope what you do next is to study Borrelia and biofilms. Leptospira and Treponema denticola are known to be able to persist inside biofilms. But there has not been published anything on Borrelia yet. No major journal has anything on it. It would meen so much to so many if you’d get that out…

Thanks for your comment. I’m not sure exactly what statement I’ve made that you are referring to. Nevertheless, I don’t see why L-form bacteria could not be able to form a biofilm. Bacteria in the L-form are simply in a different part of the microbial lifecycle and have temporarily lost their cell walls. Is a cell wall necessary to become part of biofilm community? I have not seen research along those lines.

This being said why wouldn’t L-form bacteria also form into communities in order to better protect themselves from the immune response etc? How do we know that a biofilm cannot be composed of both bacteria with cell walls and bacteria without cell walls?

So I don’t really think we need to come up with completely different terminology to describe bacteria in the L-form seeing as their characteristics are generally very similar to those of their walled counterparts and they interact with classical forms of bacteria very closely in vivo.

Best,
Amy

I have spent some time perusing your website and I complement you on your good work. As such, it is all the more important to not mar this good work by using inappropriate terminology. Specifically, the term “biofilm” refers to a community of bacteria surrounded by *Extracellular* Polymeric Substances. A tubule, or filament, or “protective sheath” formed by an L-form bacteria may be a “film” and it is no doubt biological, but it is NOT a “biofilm” as commonly defined. It is a disservice to conflate these two different phenomena. Whatever is going on with L-form bacteria deserves its own terminology so as not to introduce unnecessary confusion into the field.

Best Regards,
-JDB

I’m sorry about your illness and positive strep cultures. In my opinion you are correct – it is very likely that many of the bacteria making you ill are in a biofilm state and cannot be kill by conventional therapies. On the other hand, the MP appears to effectively break up biofilms and I think you would definitely benefit from the treatment.

I’m not sure where you live. However the best way to find a doctor in your area is to post at the following website:

http://www.curemyth1.org (Th1 refers to diseases caused by bacteria, hence the name). The patient advocates on the site, who are volunteers, can likely provide you with a list of doctors that administer the MP in your area.

If that doesn’t work out I recommend showing your current doctor or a new open-minded doctor in your area Dr. Marshall and team’s latest peer-reviewed papers and presentations. See if then you can convince them to prescribe you the necessary MP meds. The publications etc. can be found here:

http://mpkb.org/doku.php#publications_presentations

This article also give more tips on finding an MP doctor.

http://mpkb.org/doku.php/home:starting:physician:finding

Good luck and take care!
Amy

How do I find a doctor who will use the Marshall Protocol? I have Interstitial Cystitis and tested positive for Strep D, only after a week long broth culture. Based on what I have read, I think that the bacteria has formed a biofilm, which is why shorter cultures aren’t picking it up. My doctor doesn’t know a whole lot about biofilm, so I am trying to find a doctor who does, so that I can get treatment.

Thanks in advance for any help!

Megan

Thanks for writing. I know nothing about Ondamed. Are the papers you mention about it’s efficacy peer-reviewed? If so, I’d be interested in reading one.

In the meantime, I’d like to emphasize that I wouldn’t definitely not recommend using Ondamed or any other frequency therapy or supplement along with the MP. As I mentioned to Ryan before, there is a careful balance of the immune system set up in the body by the MP meds as they target bacteria, and other therapies may interfere. Also, if any therapy causes extra bacterial die-off it could lead to intolerable immunopathology when combined with the MP meds so one must be careful.

I definitely hope you look into the MP Michelle!

Best,

Amy