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	<title>Comments on: Oxytocin plugged as new feel-good drug, but implications remain murky</title>
	<atom:link href="http://bacteriality.com/2008/07/05/oxytocin/feed/" rel="self" type="application/rss+xml" />
	<link>http://bacteriality.com/2008/07/05/oxytocin/</link>
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		<title>By: Paul Albert</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-16970</link>
		<dc:creator>Paul Albert</dc:creator>
		<pubDate>Sat, 18 Apr 2009 16:38:13 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-16970</guid>
		<description>Hi Nate,

I think I see where you&#039;re coming from. Pain can be a good teacher. And, I would agree that no one is meant to live without pain. There is actually a syndrome - I heard about it on House - Congenital Insensitivity to Pain with Anhidrosis (CIPA), where a person does not feel pain. People with this disorder are prone to injure themselves, because they don&#039;t get cues about what sorts of stimuli are doing them damage.

All that said, there are some people for whom pain has &quot;taught everything that it will teach.&quot; For these people, pains meds are a sane and sensible option.

Check out &lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/17667496&quot; rel=&quot;nofollow&quot;&gt;this study&lt;/a&gt; on how Lidocaine shortens a hospital stay. Or this one, which explains how &lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/17578977&quot; rel=&quot;nofollow&quot;&gt;pain management&lt;/a&gt; may be a fundamental human right.

You can also have a look at the &lt;a href=&quot;http://mpkb.org/doku.php/home:symptoms:pain&quot; rel=&quot;nofollow&quot;&gt;Knowledge Base article&lt;/a&gt; on the subject.

Best,
Paul</description>
		<content:encoded><![CDATA[<p>Hi Nate,</p>
<p>I think I see where you&#8217;re coming from. Pain can be a good teacher. And, I would agree that no one is meant to live without pain. There is actually a syndrome &#8211; I heard about it on House &#8211; Congenital Insensitivity to Pain with Anhidrosis (CIPA), where a person does not feel pain. People with this disorder are prone to injure themselves, because they don&#8217;t get cues about what sorts of stimuli are doing them damage.</p>
<p>All that said, there are some people for whom pain has &#8220;taught everything that it will teach.&#8221; For these people, pains meds are a sane and sensible option.</p>
<p>Check out <a href="http://www.ncbi.nlm.nih.gov/pubmed/17667496" rel="nofollow">this study</a> on how Lidocaine shortens a hospital stay. Or this one, which explains how <a href="http://www.ncbi.nlm.nih.gov/pubmed/17578977" rel="nofollow">pain management</a> may be a fundamental human right.</p>
<p>You can also have a look at the <a href="http://mpkb.org/doku.php/home:symptoms:pain" rel="nofollow">Knowledge Base article</a> on the subject.</p>
<p>Best,<br />
Paul</p>
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		<title>By: Nate</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-16969</link>
		<dc:creator>Nate</dc:creator>
		<pubDate>Sat, 18 Apr 2009 16:22:10 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-16969</guid>
		<description>A lot of good information being taught on this page, My statement on Oxytocin, is that anything to good giving in a long period of time, can hurt us if not done with close supervison, due to the fact are we meant to live everyday without pain, i think pain is good part of life, it&#039;s a growth process! What do you guys think?</description>
		<content:encoded><![CDATA[<p>A lot of good information being taught on this page, My statement on Oxytocin, is that anything to good giving in a long period of time, can hurt us if not done with close supervison, due to the fact are we meant to live everyday without pain, i think pain is good part of life, it&#8217;s a growth process! What do you guys think?</p>
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		<title>By: Amy Proal</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-15941</link>
		<dc:creator>Amy Proal</dc:creator>
		<pubDate>Mon, 26 Jan 2009 17:01:48 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-15941</guid>
		<description>Thanks Inuk,

I appreciate enthusiasm in my readers!

Take care,

Amy</description>
		<content:encoded><![CDATA[<p>Thanks Inuk,</p>
<p>I appreciate enthusiasm in my readers!</p>
<p>Take care,</p>
<p>Amy</p>
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		<title>By: inuk2600</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-15934</link>
		<dc:creator>inuk2600</dc:creator>
		<pubDate>Sat, 24 Jan 2009 05:51:07 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-15934</guid>
		<description>Wow, there are so many gems in this article. You&#039;ve gone above and beyond again Amy, Thank you.</description>
		<content:encoded><![CDATA[<p>Wow, there are so many gems in this article. You&#8217;ve gone above and beyond again Amy, Thank you.</p>
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		<title>By: Amy Proal</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-13720</link>
		<dc:creator>Amy Proal</dc:creator>
		<pubDate>Tue, 14 Oct 2008 15:43:02 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-13720</guid>
		<description>Hi Paula,

The article is not intended to criticize people who might use oxytocin carefully as responsibly in lieu of a painkiller or antidepressant.

My concerns about widespread use of oxytocin stem from comments that the hormone could be sprayed on naive restaurant customers or be used by marketers to to attract people to a certain product.

Since oxytocin is a hormone, and hormonal systems are delicately balanced by numerous feedback pathways, I am just offering warning that use of the drug be approached with caution.  While oxytocin may make people feel good there is simply not enough research yet to confirm that if taken at high levels, carefully regulated hormonal pathways might not become impaired.

Vitamin D is also a hormone/secosteroid and I believe that wanton supplementation of the substance is greatly hindering individuals with chronic disease.  It would be nice to see those companies that promote oxytocin exercise more caution than the vitamin D community when it comes to allowing the public to make decisions about how to alter their hormone levels.  It seems like oxytocin might be best prescribed by a physicians rather than being directly marketed to consumers.

Best,

Amy</description>
		<content:encoded><![CDATA[<p>Hi Paula,</p>
<p>The article is not intended to criticize people who might use oxytocin carefully as responsibly in lieu of a painkiller or antidepressant.</p>
<p>My concerns about widespread use of oxytocin stem from comments that the hormone could be sprayed on naive restaurant customers or be used by marketers to to attract people to a certain product.</p>
<p>Since oxytocin is a hormone, and hormonal systems are delicately balanced by numerous feedback pathways, I am just offering warning that use of the drug be approached with caution.  While oxytocin may make people feel good there is simply not enough research yet to confirm that if taken at high levels, carefully regulated hormonal pathways might not become impaired.</p>
<p>Vitamin D is also a hormone/secosteroid and I believe that wanton supplementation of the substance is greatly hindering individuals with chronic disease.  It would be nice to see those companies that promote oxytocin exercise more caution than the vitamin D community when it comes to allowing the public to make decisions about how to alter their hormone levels.  It seems like oxytocin might be best prescribed by a physicians rather than being directly marketed to consumers.</p>
<p>Best,</p>
<p>Amy</p>
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		<title>By: Paula Carnes</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-13702</link>
		<dc:creator>Paula Carnes</dc:creator>
		<pubDate>Mon, 13 Oct 2008 04:41:25 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-13702</guid>
		<description>Amy, I assume you have had an orgasm. I doubt you have breastfed. Let me hasten to add that I have done both for extensive periods of time. If a spray would give me that level of joy I would happily use the product. Both of these experiences, as you have noted, increase natural levels of oxytocin. Neither of these experiences would tend to cause someone to join a cult or allow a tiger in the front door. (Well, the orgasm might cause you to marry a fool, but that is a real risk even if you don&#039;t use oxytocin spray.) Oxytocin would be infinitely safer than the current antidepressants and anti-anxiety meds. It would be great if all of us were completely cured of our infections. Meanwhile oxytocin is a nice safe treatment for some very sick folks.</description>
		<content:encoded><![CDATA[<p>Amy, I assume you have had an orgasm. I doubt you have breastfed. Let me hasten to add that I have done both for extensive periods of time. If a spray would give me that level of joy I would happily use the product. Both of these experiences, as you have noted, increase natural levels of oxytocin. Neither of these experiences would tend to cause someone to join a cult or allow a tiger in the front door. (Well, the orgasm might cause you to marry a fool, but that is a real risk even if you don&#8217;t use oxytocin spray.) Oxytocin would be infinitely safer than the current antidepressants and anti-anxiety meds. It would be great if all of us were completely cured of our infections. Meanwhile oxytocin is a nice safe treatment for some very sick folks.</p>
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		<title>By: Amy Proal</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-9559</link>
		<dc:creator>Amy Proal</dc:creator>
		<pubDate>Fri, 11 Jul 2008 18:11:31 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-9559</guid>
		<description>Hi Ceredwyn,

While the depression and rise in symptoms often seen postpartum may be due to in part oxytocin withdrawl, women also generally experience an increase in disease symptoms after a pregnancy due to the fact that the Th1 pathogens are able to spread with greater ease during gestation.

A woman&#039;s level of 1,25-D is naturally up-regulated during pregnancy, and since 1,25-D is already high in patients with inflammatory disease due to VDR blockage, combined high levels of 1,25-D proceed to block antimicrobial peptide production via the nuclear receptors.  This means that during pregnancy, women are more increasingly immunocompromised and can more easily pick up the Th1 pathogens.

So after giving birth, women often start to display more signs of the mental and physical diseases caused by the Th1 pathogens.  You&#039;ve probably noted that women often seem to become increasingly ill with each subsequent pregnancy.

This article discusses 1,25-D, immunosuppression, and pregnancy in greater depth:

http://bacteriality.com/2008/03/09/cognitive-dysfunction/

Best

Amy</description>
		<content:encoded><![CDATA[<p>Hi Ceredwyn,</p>
<p>While the depression and rise in symptoms often seen postpartum may be due to in part oxytocin withdrawl, women also generally experience an increase in disease symptoms after a pregnancy due to the fact that the Th1 pathogens are able to spread with greater ease during gestation.</p>
<p>A woman&#8217;s level of 1,25-D is naturally up-regulated during pregnancy, and since 1,25-D is already high in patients with inflammatory disease due to VDR blockage, combined high levels of 1,25-D proceed to block antimicrobial peptide production via the nuclear receptors.  This means that during pregnancy, women are more increasingly immunocompromised and can more easily pick up the Th1 pathogens.</p>
<p>So after giving birth, women often start to display more signs of the mental and physical diseases caused by the Th1 pathogens.  You&#8217;ve probably noted that women often seem to become increasingly ill with each subsequent pregnancy.</p>
<p>This article discusses 1,25-D, immunosuppression, and pregnancy in greater depth:</p>
<p><a href="http://bacteriality.com/2008/03/09/cognitive-dysfunction/" rel="nofollow">http://bacteriality.com/2008/03/09/cognitive-dysfunction/</a></p>
<p>Best</p>
<p>Amy</p>
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		<title>By: Ceredwyn Alexander</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-9543</link>
		<dc:creator>Ceredwyn Alexander</dc:creator>
		<pubDate>Fri, 11 Jul 2008 14:17:33 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-9543</guid>
		<description>One only needs to look at the panoply of postpartum mental disorders to see the possibility of withdrawal reactions.  Especially in women who don&#039;t breastfeed and therefore experience an especially sudden drop in their oxytocin levels.  

No woman (or at least I&#039;ve never met or heard of them) escapes the &quot;baby blues&quot; and many experience mental illnesses that can last from weeks to years.  Illnesses that run the gamut from moderate depression to florid psychosis complete with homicidal tendencies(anybody else remember Andrea Yates?).

A big part of my practice consisted of providing social support through this time.  I really don&#039;t want to have to open a clinic for &quot;oxy-addicts&quot;</description>
		<content:encoded><![CDATA[<p>One only needs to look at the panoply of postpartum mental disorders to see the possibility of withdrawal reactions.  Especially in women who don&#8217;t breastfeed and therefore experience an especially sudden drop in their oxytocin levels.  </p>
<p>No woman (or at least I&#8217;ve never met or heard of them) escapes the &#8220;baby blues&#8221; and many experience mental illnesses that can last from weeks to years.  Illnesses that run the gamut from moderate depression to florid psychosis complete with homicidal tendencies(anybody else remember Andrea Yates?).</p>
<p>A big part of my practice consisted of providing social support through this time.  I really don&#8217;t want to have to open a clinic for &#8220;oxy-addicts&#8221;</p>
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		<title>By: Amy Proal</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-9474</link>
		<dc:creator>Amy Proal</dc:creator>
		<pubDate>Thu, 10 Jul 2008 20:05:13 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-9474</guid>
		<description>Hi Ceredwyn,

Well, there you go..it appears you&#039;ve already witnessed some of the murky implications I envision from oxytocin supplementation.  Thanks for sharing your experience.  I would expect that people might &quot;crash&quot; if they tried to immediately stop a substance that was artificially enhancing their mood.

I can definitely see oxytocin being abused in order to make people more suggestible.  The idea of spraying it on restaurant patrons is, in my opinion, already in that league.  &quot;Honey, do you want dessert?&quot;  &quot;Yes, I think I&quot;ll have five of those huge chocolate cakes...this place is great!&quot;  Then later on &quot;Wait a second, I just gained five pounds..what the &amp;#@#!&quot;

Best,

Amy</description>
		<content:encoded><![CDATA[<p>Hi Ceredwyn,</p>
<p>Well, there you go..it appears you&#8217;ve already witnessed some of the murky implications I envision from oxytocin supplementation.  Thanks for sharing your experience.  I would expect that people might &#8220;crash&#8221; if they tried to immediately stop a substance that was artificially enhancing their mood.</p>
<p>I can definitely see oxytocin being abused in order to make people more suggestible.  The idea of spraying it on restaurant patrons is, in my opinion, already in that league.  &#8220;Honey, do you want dessert?&#8221;  &#8220;Yes, I think I&#8221;ll have five of those huge chocolate cakes&#8230;this place is great!&#8221;  Then later on &#8220;Wait a second, I just gained five pounds..what the &#@#!&#8221;</p>
<p>Best,</p>
<p>Amy</p>
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		<title>By: Ceredwyn Alexander</title>
		<link>http://bacteriality.com/2008/07/05/oxytocin/comment-page-1/#comment-9353</link>
		<dc:creator>Ceredwyn Alexander</dc:creator>
		<pubDate>Wed, 09 Jul 2008 14:17:17 +0000</pubDate>
		<guid isPermaLink="false">http://bacteriality.com/?p=229#comment-9353</guid>
		<description>I used to be a doula (a birth and labor assistant) and I wonder what would happen if large swaths of the population were given oxytocin.  Post birth, women are docile and extremely suggestable.  It fosters bonding with their child and makes their tribe more likely to take care of them.  It also makes them vulnerable to ad campaigns and any fool with a theory.  Then we see the oxytocin withdrawl &quot;crash&quot; of the &quot;baby blues&quot; in about three days.  Sometimes becoming full blown postpartum depression.

So we have a drug with that causes docility and suggestibility, followed by possibly severe withdrawl.  Yeah, I want to be part of that.</description>
		<content:encoded><![CDATA[<p>I used to be a doula (a birth and labor assistant) and I wonder what would happen if large swaths of the population were given oxytocin.  Post birth, women are docile and extremely suggestable.  It fosters bonding with their child and makes their tribe more likely to take care of them.  It also makes them vulnerable to ad campaigns and any fool with a theory.  Then we see the oxytocin withdrawl &#8220;crash&#8221; of the &#8220;baby blues&#8221; in about three days.  Sometimes becoming full blown postpartum depression.</p>
<p>So we have a drug with that causes docility and suggestibility, followed by possibly severe withdrawl.  Yeah, I want to be part of that.</p>
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